Recent advances and challenges in  biotechnology application; biotechnological techniques, such as rDNA technology, DNA cloning and expression of cloned DNA, DNA sequence information, new biological targets for drug development and novel drug screening strategies; novel biological agents such as antibodies, antisense gene therapy, oligo-nucleotide therapy (PNA), gene therapy, new multivalent vaccines, insulin production, monoclonal antibodies, biologic immune response modifiers; biological systems used in commercial production of biopharmaceuticals and their applications. (2 Credit hours)