Researchers develop natural antibiotics against skin disease

Antimicrobial resistance is rising, making it difficult to treat some bacteria-based skin diseases and infections. However, a group of researchers from Birzeit University, An-Najah National University, and Beit-Jala Pharmaceutical Company recognized the need to develop a formula that overcomes microbial resistance in skin infections.

In-vitro antibacterial activity was determined by measuring the diameter of the zone of inhibition for bacteria, yeast, and FRSA samples on an agar plate. With the use of natural products and ions, the team created a cream formula composed of natural products, including oleuropein, thyme oil, zinc, sulfate, and copper sulfate, complexed with fusidic ions. This marks the first time the formula was developed as a cream.

The team comprised Hani Shtaya (Naseef), Yousef Sahoury, Moammal Qurt, Israr Sabri, Abdualla Rabaa, and Abdallah Abu Khalil, associate professors at Birzeit University’s Department of Pharmacy; Mohammad Farraj, researcher and student at the university’s master’s program in Clinical Laboratory Science; Nidal Jaradat, associate professor at the Department of Pharmacy at An-Najah National University, and Mahmoud Sbeih, representing Beit-Jala Pharmaceutical Company- Quality Control Department.

The new formula has the potential to compound with new natural antibiotic agents and contains excellent homogeneity for the cream formulation, good spreadability, and no interactions with the other ingredients in the cream.

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