Basic designs of epidemiological studies, Odds ratio, Relative risk, Confounding and interaction ratios, Cohort studies, Case-Control studies, Matched case-control studies, Clinical trials, Crossover design and allocation of treatments, Sample size determination, Data analysis of survival and risk, Nonparametric methods, Kaplan-Meyer estimation of survival function, Parametric models including proportional risk model and Cox model, Application using Statistical softwares.