AWARDS

 June 2019, The best medical research in Palestine 2019

The Higher Council for Innovation and Excellence - Mohammed Al-Masroji Award for Applied Research and Creative Ideas “masking the bitter taste of guaifenesin, a medication used to treat coughs and congestion”.

Feb. 2020, The most active research group 2019

Al-Quds University - Deanship of Scientific Research, Drug Design and Discovery Research Group - Pharmacy College.

FUNDED PROJECTS 

Pharmaceutical Dossier Development - Hikma Pharmaceutical Co. (40,000 $)

Jerusalem employee training – Jerusalem Pharmaceutical Co. (11,500 $)

Cosmetics and cream industrial training course – first cycle (2,700$)

Cosmetics and cream industrial training course – second cycle (2,600

BeePharm Food Supplement development - Australia (6,500 $)

EDUCATION

• Ph.D. In Medicinal chemistry and pharmaceutical technology, University of Basilicata – Italy

• M.Sc. In Chemical Applied Industrial Technology, Al-Quds University - Palestine 

• B.Sc. In Chemistry, Al-Quds University – Palestine

 EXPERIENCE

• Acting Director of Sameh Darwazeh Institute of Industrial Pharmacy, Birzeit University. 

  Palestine, Jan 2019 until now.

• Drug Design Scientific Researcher, Universita Degli Studi Della Basilicata

  Italy, Dec. 2014 – Nov. 2017

• Lab. Instructor, Photochemistry Lab., Universita Degli Studi Della Basilicata

  Italy, May 2016 – March 2017

• Computational Chemistry Research Assistant, Department of Bioorganic Chemistry, Al-Quds University.

  Palestine, Jan. 2017 – Oct. 2017

• Drug Developments Scientific Researcher, Pharmacy College, Al-Quds University

  Palestine, March 2012 – Dec. 2014

• Production Supervisor, Beit Jala Pharmaceutical Company

  Palestine, June 2010 – March 2012

• Volunteer in Department of Science chemical laboratories, Al-Quds University

  Palestine, Sep 2007– July 2008

RESEARCH INTEREST & SKILLS

Qualification and experience revolve around the pharmaceutical industry, pharmaceutical quality control and validation, mainly in:

• Stability Storage and Testing and Accelerated Ageing Studies
• Extractables and Leachables
• Method Development and Validation
• QC (batch release) and Raw Materials Testing
• Residual Solvent Testing
• Water Analysis
• GMP / GLP
• Heavy Metals Testing
• Cleaning and Sterilization Validation of Reusable Medical Devices

PUBLICATION

• Understanding the Risks of Diffusion of Cyanobacteria Toxins in Rivers, Lakes, and Potable Water. Toxins 2023, 15(9), 582.
• Stability and Removal of Commonly Used Drugs in Environmental Water and Wastewater. Journal of Environmental Science and Engineering 2023, 16.
• Skin Pigmentation Types, Causes and Treatment—A Review. Molecules 2023, 28(12), 4839. View
• Antifungal and antibacterial activities of isolated marine compounds. Toxins 2023, 15(2), 93. View
• Classification, Toxicity and Bioactivity of Natural Diterpenoid Alkaloids. Molecules 2021, 26(13), 4103. View
• The Biological Activity of Natural Alkaloids against Herbivores, Cancerous Cells and Pathogens.Toxins 2019, 11(11), 656. View
• Bitterless guaifenesin prodrugs—design, synthesis, characterization, in vitro kinetics, and bitterness studies, October 2018, Chemical Biology & Drug Design journal, 92 (4).View
• Chapter 105 - Solanine (Nightshade Glycoalkaloids), Handbook of Foodborne Diseases, 1115 to 1122.View
• Anti-cancer Pro-drugs-Three Decades of Design, July 2015, World Journal of Pharmacy & Pharmaceutical Sciences , 4(7), 1751-1779.View
• Mefenamic acid Pro-drugs and codrugs – Two Decades of Development, June 2015, World Journal of Pharamaceutical Research, 4(6), 2408- 2429.View
• Diclofenac drugs and prodrugs – three decades of design. May 2015, World Journal of Pharmaceutical Research, 4(7),1960- 1982.View
• Removal of Aspirin, Salicylic Acid, Paracetamol and p-Aminophenol by Advanced Membrane technology Activated Charcoal and Clay Micelles Complex. May 2015, Case Studies Journal, 4(5),74-111.View
• Removal of Antibacterial Agents by Advanced Membrane Technology andODUMA-Micelle-Clay Complex. June 2015, Case Studies Journal, 4(5), 143-164.View
• Chapter 4 - Targeted Prodrugs, Prodrugs Design – A New Era, 139-176. View

Implementation of mini-research projects during study years, and ability to propose creative ideas in the industries and pharmaceutical analysis that generates financial support through relations with local and Italian pharmaceutical factories and through research centers in Italian and European universities.

A Five years’ work experience as a research assistant at Al Quds University in Drug Discovery Labs, Mr. Thawabteh’s responsibility included tasks related to chemical synthesis and purification of novel drugs and prodrugs, identification and characterization of unknown compounds using spectroscopic and chromatographic techniques, HPLC, LC-MS, GC, UV-VIS, FT-IR and NMR

Design, synthesis, characterization, In vitro and In vivo studies of prodrug systems to be used for the delivery for certain drugs that have poor water solubility or/and have low bioavailability using AB initio, DFT, semi- empirical, molecular mechanics as well as molecular dynamics and conformational dynamics methods.

Design and installing linkers to be used for masking bitter taste of drugs that contain a hydroxyl or amine groups (antimalarial, anti- hypertension, anti-bleeding, antibacterial and anticancer drugs) using DFT calculation methods.

Computational chemistry software’s: Gaussian 09, GaussView 6, Molden, ArgusLab, PerkinElmer ChemDraw and ChemOffice. Microsoft Office: Microsoft word, Excel, PowerPoint, Outlook and OneNote. SigmaPlot: Scientific Data Analysis and Graphing Software, Mestrelab Mnova NMR software.