Ph.D. In Pharmaceutical chemistry and technology, University of Basilicata – Italy
M.Sc. In Chemical Applied Industrial Technology, Al-Quds University - Palestine
B.Sc. In Chemistry, Al-Quds University – Palestine
Acting Director of Sameh Darwazeh Institute of Industrial Pharmacy, Birzeit University.
Palestine, Jan 2019 until now.
Drug Design Scientific Researcher, Universita Degli Studi Della Basilicata
Italy, Dec. 2014 – Nov. 2017
Lab. Instructor, Photochemistry Lab., Universita Degli Studi Della Basilicata
Italy, May 2016 – March 2017
Computational Chemistry Research Assistant, Department of Bioorganic Chemistry, Al-Quds University.
Palestine, Jan. 2017 – Oct. 2017
Drug Developments Scientific Researcher, Pharmacy College, Al-Quds University
Palestine, March 2012 – Dec. 2014
Production Supervisor, Beit Jala Pharmaceutical Company
Palestine, June 2010 – March 2012
Volunteer in Department of Science chemical laboratories, Al-Quds University
Palestine, Sep 2007– July 2008
RESEARCH INTEREST & SKILLS
Qualification and experience revolve around the pharmaceutical industry, pharmaceutical quality control and validation, mainly in:
- Stability Storage and Testing and Accelerated Ageing Studies
- Extractables and Leachables
- Method Development and Validation
- QC (batch release) and Raw Materials Testing
- Residual Solvent Testing
- Water Analysis
- GMP / GLP
- Heavy Metals Testing
- Cleaning and Sterilization Validation of Reusable Medical Devices
Implementation of mini-research projects during study years, and ability to propose creative ideas in the industries and pharmaceutical analysis that generates financial support through relations with local and Italian pharmaceutical factories and through research centers in Italian and European universities.
A Five years’ work experience as a research assistant at Al Quds University in Drug Discovery Labs, Mr. Thawabteh’s responsibility included tasks related to chemical synthesis and purification of novel drugs and prodrugs, identification and characterization of unknown compounds using spectroscopic and chromatographic techniques, HPLC, LC-MS, GC, UV-VIS, FT-IR and NMR
Design, synthesis, characterization, In vitro and In vivo studies of prodrug systems to be used for the delivery for certain drugs that have poor water solubility or/and have low bioavailability using AB initio, DFT, semi- empirical, molecular mechanics as well as molecular dynamics and conformational dynamics methods.
Design and installing linkers to be used for masking bitter taste of drugs that contain a hydroxyl or amine groups (antimalarial, anti- hypertension, anti-bleeding, antibacterial and anticancer drugs) using DFT calculation methods.
Computational chemistry software’s: Gaussian 09, GaussView 6, Molden, ArgusLab, PerkinElmer ChemDraw and ChemOffice. Microsoft Office: Microsoft word, Excel, PowerPoint, Outlook and OneNote. SigmaPlot: Scientific Data Analysis and Graphing Software, Mestrelab Mnova NMR software.
Bitterless guaifenesin prodrugs—design, synthesis, characterization, in vitro kinetics, and bitterness studies, October 2018, Chemical Biology & Drug Design journal, 92 (4). View
Chapter 105 - Solanine (Nightshade Glycoalkaloids), Handbook of Foodborne Diseases, 1115 to 1122. View
Anti-cancer Pro-drugs-Three Decades of Design, July 2015, World Journal of Pharmacy & Pharmaceutical Sciences , 4(7), 1751-1779. View
Mefenamic acid Pro-drugs and codrugs – Two Decades of Development, June 2015, World Journal of Pharamaceutical Research, 4(6), 2408- 2429. View
Diclofenac drugs and prodrugs – three decades of design. May 2015, World Journal of Pharmaceutical Research, 4(7),1960- 1982. View
Removal of Aspirin, Salicylic Acid, Paracetamol and p-Aminophenol by Advanced Membrane technology Activated Charcoal and Clay Micelles Complex. May 2015, Case Studies Journal, 4(5), 74-111. View
Removal of Antibacterial Agents by Advanced Membrane Technology and ODUMA-Micelle-Clay Complex. June 2015, Case Studies Journal, 4(5), 143-164. View
Chapter 4 - Targeted Prodrugs, Prodrugs Design – A New Era, 139-176. View