The course provides a description of physicochemical and biopharmaceutical aspects involved in the design and formulation that affect drug performance and development of pharmaceutical dosage forms. In addition, this course covers the basic concepts and principles of pharmacokinetics and mathematical expressions that influence and characterize drug liberation, absorption, distribution, metabolism and elimination. Topics covered include an introduction to pharmacokinetic models, demonstration of the prediction of drug concentration after various modes of administration, discussion of the physicochemical and patient related factors affecting drug absorption, bioavailability and bioequivalence and drug distribution.
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